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Astragalus membranaceus and Cinnamomum cassia Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/β-Catenin Signaling Pathway

In normal rats maintained on a four-month KD, combined structural MRI, spectroscopy, and tractography revealed increased brain glutamine, glutamate, GSH, and N-acetylaspartate together with reconfigured connectivity in striatum and hippocampal formation—evidence for durable neurobiological adaptations of glutamatergic/redox metabolism and white matter architecture under sustained ketosis [64]

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Under normal conditions in senescent cells, FOXO4 interacts with p53 and retains it in the nucleus, preventing p53 from translocating to mitochondria and executing its intrinsic pro-apoptotic programme